
The Goldilocks Problem in Gene Drives: Finding Cas9 Expression That Is Just Right
Gene drives are among the most ambitious tools in genetic engineering: self-perpetuating DNA constructs that bias their own inheritance, capable of spreading a modified trait through an entire wild population. A well-designed gene drive could render malaria-carrying mosquitoes incapable of transmitting the parasite, or suppress invasive rodents that devastate island ecosystems. But even the most […]









