Sleep

Patients on maintenance hemodialysis carry a double burden: poor sleep quality and moderate-to-severe fatigue, and the two conditions reinforce each other in a cycle that biochemical markers and medication load help drive. A new observational study from three public hospitals in Turkey, published in the International Journal of Artificial Organs, assessed 78 patients receiving regular […]

Insomnia does more than ruin a night’s rest, it may actively worsen sepsis-induced acute lung injury through a specific immune pathway. Researchers have identified the protein tyrosine phosphatase PTPN6 as a critical molecular bridge connecting poor sleep to pulmonary inflammation in sepsis. The study, published in Frontiers in Immunology, integrated Mendelian randomization, transcriptomics, single-cell RNA […]

Insomnia affects 38.2% of adults aged 80 years and older, according to a new cross-sectional study from Turkey, and the condition is closely tied to factors that clinicians can identify and address. The study, published in the Revista da Associação Médica Brasileira, screened 419 patients aged 80 and older at the Advanced Age Unit of […]

A new randomized trial from Guangzhou University of Chinese Medicine will test whether a wearable low-level laser device can match or outperform traditional manual acupuncture for chronic insomnia, without the needles, the practitioner visits, or the needling discomfort. The trial, published as a study protocol in Frontiers in Psychiatry, plans to enroll 106 adults ages […]

A new clinical rating scale designed to capture the breadth and severity of early-stage synucleinopathy has shown good to excellent reliability in a large multicenter cohort of patients with REM sleep behavior disorder (RBD), according to a study published in Neurology. The Prodromal Synucleinopathy Rating Scale (PSRS) may become a key tool for upcoming clinical […]

Three weeks of wrist actigraphy in patients with suspected or confirmed Cushing’s syndrome revealed surprisingly few sleep and circadian differences compared with controls, according to an exploratory study from LMU University Hospital Munich. The one exception was chronotype: patients with active Cushing’s had significantly earlier sleep timing. The findings challenge assumptions about how readily wearable […]

The brains of people with insomnia disorder show a reduced ability to resist auditory disturbances during sleep, particularly in deep sleep, according to a study published in iScience. The work introduces the concept of “sleep resilience” as a measurable trait and suggests that objective EEG markers of neural instability could help characterize insomnia beyond subjective […]

Just 96 hours of REM (paradoxical) sleep deprivation shrinks rat testicles by roughly 28%, stiffens testicular tissue by nearly 50%, and severely impairs sperm motility and morphology, according to a new study from Anhui Medical University in China. Seven days of recovery sleep partially reversed the tissue stiffness and restored some sperm movement, but sperm […]

A path analysis of 270 Argentinean university students reveals two distinct routes by which social media use undermines cognitive performance: one through bedtime smartphone use and disrupted sleep, the other through smartphone dependence itself. What they found Researchers at Pontificia Universidad Catolica Argentina assessed problematic smartphone use (PSU), social media frequency, bedtime smartphone use, sleep […]

Emmanuel Mignot, the Stanford researcher who co-discovered orexin and its role in narcolepsy, argues in a new review that the standard diagnostic test for hypersomnia, the Multiple Sleep Latency Test (MSLT), has a high false-positive rate outside of narcolepsy type 1 and proposes returning to four historically grounded clinical subtypes to guide diagnosis and treatment. […]